by Christina Sarich
According to studies that were published in an issue of Life Sciences, artemesinin – a derivative of the wormwood plant used in Chinese Medicine - can kill 98% of breast cancer cells in less than 16 hours. The
herb used alone caused a 28% reduction in breast cancer cells, but when
paired with iron, sweet
wormwood was able to eradicate cancer almost
entirely. What’s more, normal cells were not negatively affected in the experiment by this treatment.
Artemisinin has been used in the past as a powerful anti-malarial
herb, but it now has been proven to be a cancer-fighter, too. When
subjects in the published study were
given an iron supplement, which often accumulates in the breast tissue
but especially so in cancerous cells, the artemisinin was able to
selectively target ‘bad’ cells and leave ‘good’ cells alone.
“Taken together, our results demonstrate that the artemisinin disruption of E2F1 transcription factor expression mediates the cell cycle arrest of human breast cancer cells and represents a critical transcriptional pathway by which artemisinin controls human reproductive cancer cell growth.”
Read: Watercress Found to Block Breast Cancer Cell Growth
Iron accumulates in cancerous cells due to special receptors that
help them in cell division, called transferrin receptors. Normal cells
likely have these receptors as well, but cancerous cells have them in
greater abundance, and thus can be targeted by the iron-artemisinin
combination, like a 1-2 punch.
There have been many experiments now that prove this sweet wormwood
derivative can effectively eradicate disease in the presence of iron.
The extract has been used for thousand of years in China to treat
malaria. The malaria parasite cannot live in the presence of artemisinin
because they are iron-rich, but the treatment works just as well for
cancerous cells, too. Bioengineers Henry Lai and Narendra Singh of the
University of Washington, Seattle were the scientists who initially made
this discovery. This is yet another example of a natural herb causing
cancerous cell apoptosis.
While the sweet wormwood extract has been somewhat difficult to
obtain for a fair price for countless years, it is now on its way to
being mass-produced by biotech. Will the result be positive and
promising?
“It’s the volatility that really makes the supply chain for this life-saving drug just a complete train wreck,” says Jack Newman, chief scientific officer of the California-based biotech firm Amyris. ”When we first started talking about this,” Newman says, “we gave it 1,000 to 1 odds of ever working. “
French drugmaker Sanofi is expected to make 50 to 60 tons of
artemisinin each year, striving to supply enough demand for the global
market.
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